VEGF: significant throughout breast tumor development
VEGF is expressed throughout the tumor life cycle
In women presenting with a first diagnosis of breast cancer, approximately 60% of the tumors express only VEGF. However, breast cancers in some patients may express up to 6 angiogenic proteins.6
Adapted from Folkman 2005.
While many pro-angiogenic factors have been identified in breast cancer, vascular endothelial growth factor (VEGF) appears to be the only factor expressed throughout the entire life cycle of a breast tumor.6 The clinical significance of this finding is unknown.
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